Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

Resistance to chemotherapy in ovarian cancer is poorly understood. Evolutionary models of cancer predict that, following treatment, resistance emerges either due to outgrowth of an intrinsically resistant sub-clone, or evolves in residual disease under the selective pressure of treatment. To investi...

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Detalles Bibliográficos
Autores principales: Cooke, Susanna L, Ng, Charlotte KY, Melnyk, Nataliya, Garcia, Maria J, Hardcastle, Tom, Temple, Jillian, Langdon, Simon, Huntsman, David, Brenton, James D
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933510/
https://www.ncbi.nlm.nih.gov/pubmed/20581869
http://dx.doi.org/10.1038/onc.2010.245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933510/
https://www.ncbi.nlm.nih.gov/pubmed/20581869
http://dx.doi.org/10.1038/onc.2010.245

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