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Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma
Resistance to chemotherapy in ovarian cancer is poorly understood. Evolutionary models of cancer predict that, following treatment, resistance emerges either due to outgrowth of an intrinsically resistant sub-clone, or evolves in residual disease under the selective pressure of treatment. To investi...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933510/ https://www.ncbi.nlm.nih.gov/pubmed/20581869 http://dx.doi.org/10.1038/onc.2010.245 |