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Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB

To gain global insights into the role of the well-known repressive splicing regulator PTB we analyzed the consequences of PTB knockdown in HeLa cells using high-density oligonucleotide splice-sensitive microarrays. The major class of identified PTB-regulated splicing event was PTB-repressed cassette...

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Detalles Bibliográficos
Autores principales: Llorian, Miriam, Schwartz, Schraga, Clark, Tyson A., Hollander, Dror, Tan, Lit-Yeen, Spellman, Rachel, Gordon, Adele, Schweitzer, Anthony C., de la Grange, Pierre, Ast, Gil, Smith, Christopher WJ
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933513/
https://www.ncbi.nlm.nih.gov/pubmed/20711188
http://dx.doi.org/10.1038/nsmb.1881