Retinoic acid accelerates downregulation of the Xist repressor, Oct4, and increases the likelihood of Xist activation when Tsix is deficient

BACKGROUND: Imbalances in X-linked gene dosage between the sexes are resolved by transcriptionally silencing one of two X-chromosomes in female cells of the early mammalian embryo. X-inactivation is triggered by expression of the non-coding Xist gene. In turn, Xist is dually regulated by the antisen...

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Detalles Bibliográficos
Autores principales: Ahn, Janice Y, Lee, Jeannie T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933617/
https://www.ncbi.nlm.nih.gov/pubmed/20727175
http://dx.doi.org/10.1186/1471-213X-10-90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933617/
https://www.ncbi.nlm.nih.gov/pubmed/20727175
http://dx.doi.org/10.1186/1471-213X-10-90

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