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Deregulated expression of hnRNP A/B proteins in human non-small cell lung cancer: parallel assessment of protein and mRNA levels in paired tumour/non-tumour tissues

BACKGROUND: Heterogeneous nuclear ribonucleoproteins (hnRNPs) of the A/B type (hnRNP A1, A2/B1, A3) are highly related multifunctional proteins participating in alternative splicing by antagonising other splicing factors, notably ASF/SF2. The altered expression pattern of hnRNP A2/B1 and/or splicing...

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Detalles Bibliográficos
Autores principales: Boukakis, Georgios, Patrinou-Georgoula, Meropi, Lekarakou, Maria, Valavanis, Christos, Guialis, Apostolia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933625/
https://www.ncbi.nlm.nih.gov/pubmed/20716340
http://dx.doi.org/10.1186/1471-2407-10-434