THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves

THAP-family C(2)CH zinc-coordinating DNA-binding proteins function in diverse eukaryotic cellular processes, such as transposition, transcriptional repression, stem-cell pluripotency, angiogenesis and neurological function. To determine the molecular basis for sequence-specific DNA recognition by TH...

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Detalles Bibliográficos
Autores principales: Sabogal, Alex, Lyubimov, Artem Y., Corn, Jacob E., Berger, James M., Rio, Donald C.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933787/
https://www.ncbi.nlm.nih.gov/pubmed/20010837
http://dx.doi.org/10.1038/nsmb.1742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933787/
https://www.ncbi.nlm.nih.gov/pubmed/20010837
http://dx.doi.org/10.1038/nsmb.1742

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