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THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves
THAP-family C(2)CH zinc-coordinating DNA-binding proteins function in diverse eukaryotic cellular processes, such as transposition, transcriptional repression, stem-cell pluripotency, angiogenesis and neurological function. To determine the molecular basis for sequence-specific DNA recognition by TH...
Autores principales: | Sabogal, Alex, Lyubimov, Artem Y., Corn, Jacob E., Berger, James M., Rio, Donald C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933787/ https://www.ncbi.nlm.nih.gov/pubmed/20010837 http://dx.doi.org/10.1038/nsmb.1742 |
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