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LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection

POT1 is the single stranded telomeric overhang binding protein, and is part of the shelterin complex, a group of six proteins essential for proper telomere function. The reduction or abrogation of POT1 DNA binding activity in mammalian cells results in telomere elongation, or activation of the ATR D...

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Detalles Bibliográficos
Autores principales: Sheppard, Samantha A., Loayza, Diego
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933890/
https://www.ncbi.nlm.nih.gov/pubmed/20634563