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Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model

S100B promotes development and maturation in the mammalian brain. However, prolonged or extensive exposure can lead to neurodegeneration. Two important functions of S100B in this regard, are its role in the development and plasticity of the serotonergic neurotransmitter system, and its role in the c...

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Detalles Bibliográficos
Autores principales: Shapiro, Lee A., Bialowas-McGoey, Lynn A., Whitaker-Azmitia, Patricia M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933893/
https://www.ncbi.nlm.nih.gov/pubmed/20827311
http://dx.doi.org/10.1155/2010/153657