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Over-expression of ST3Gal-I promotes mammary tumorigenesis

Changes in glycosylation are common in malignancy, and as almost all surface proteins are glycosylated, this can dramatically affect the behavior of tumor cells. In breast carcinomas, the O-linked glycans are frequently truncated, often as a result of premature sialylation. The sialyltransferase ST3...

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Detalles Bibliográficos
Autores principales: Picco, Gianfranco, Julien, Sylvain, Brockhausen, Inka, Beatson, Richard, Antonopoulos, Aristotelis, Haslam, Stuart, Mandel, Ulla, Dell, Anne, Pinder, Sarah, Taylor-Papadimitriou, Joyce, Burchell, Joy
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934706/
https://www.ncbi.nlm.nih.gov/pubmed/20534593
http://dx.doi.org/10.1093/glycob/cwq085