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Novel expression signatures identified by transcriptional analysis of separated leucocyte subsets in systemic lupus erythematosus and vasculitis

OBJECTIVE: To optimise a strategy for identifying gene expression signatures differentiating systemic lupus erythematosus (SLE) and antineutrophil cytoplasmic antibody-associated vasculitis that provide insight into disease pathogenesis and identify biomarkers. METHODS: 44 vasculitis patients, 13 SL...

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Detalles Bibliográficos
Autores principales: Lyons, Paul A, McKinney, Eoin F, Rayner, Tim F, Hatton, Alexander, Woffendin, Hayley B, Koukoulaki, Maria, Freeman, Thomas C, Jayne, David R W, Chaudhry, Afzal N, Smith, Kenneth G C
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935323/
https://www.ncbi.nlm.nih.gov/pubmed/19815495
http://dx.doi.org/10.1136/ard.2009.108043