Calcium Regulation of EGF-Induced ERK5 Activation: Role of Lad1-MEKK2 Interaction

The ERK5 cascade is a MAPK pathway that transmits both mitogenic and stress signals, yet its mechanism of activation is not fully understood. Using intracellular calcium modifiers, we found that ERK5 activation by EGF is inhibited both by the depletion and elevation of intracellular calcium levels....

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Detalles Bibliográficos
Autores principales: Yao, Zhong, Yoon, Seunghee, Kalie, Eyal, Raviv, Ziv, Seger, Rony
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935384/
https://www.ncbi.nlm.nih.gov/pubmed/20830310
http://dx.doi.org/10.1371/journal.pone.0012627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935384/
https://www.ncbi.nlm.nih.gov/pubmed/20830310
http://dx.doi.org/10.1371/journal.pone.0012627

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