Dissecting the Relation between a Nuclear Receptor and GATA: Binding Affinity Studies of Thyroid Hormone Receptor and GATA2 on TSHβ Promoter

BACKGROUND: Much is known about how genes regulated by nuclear receptors (NRs) are switched on in the presence of a ligand. However, the molecular mechanism for gene down-regulation by liganded NRs remains a conundrum. The interaction between two zinc-finger transcription factors, Nuclear Receptor a...

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Detalles Bibliográficos
Autores principales: Figueira, Ana Carolina Migliorini, Polikarpov, Igor, Veprintsev, Dmitry, Santos, Guilherme Martins
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935386/
https://www.ncbi.nlm.nih.gov/pubmed/20838640
http://dx.doi.org/10.1371/journal.pone.0012628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935386/
https://www.ncbi.nlm.nih.gov/pubmed/20838640
http://dx.doi.org/10.1371/journal.pone.0012628

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