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Dynamic deterministic effects propagation networks: learning signalling pathways from longitudinal protein array data

Motivation: Network modelling in systems biology has become an important tool to study molecular interactions in cancer research, because understanding the interplay of proteins is necessary for developing novel drugs and therapies. De novo reconstruction of signalling pathways from data allows to u...

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Detalles Bibliográficos
Autores principales: Bender, Christian, Henjes, Frauke, Fröhlich, Holger, Wiemann, Stefan, Korf, Ulrike, Beißbarth, Tim
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935402/
https://www.ncbi.nlm.nih.gov/pubmed/20823327
http://dx.doi.org/10.1093/bioinformatics/btq385