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Prototypes of elementary functional loops unravel evolutionary connections between protein functions

Motivation: Earlier studies of protein structure revealed closed loops with a characteristic size 25–30 residues and ring-like shape as a basic universal structural element of globular proteins. Elementary functional loops (EFLs) have specific signatures and provide functional residues important for...

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Detalles Bibliográficos
Autores principales: Goncearenco, Alexander, Berezovsky, Igor N.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935408/
https://www.ncbi.nlm.nih.gov/pubmed/20823313
http://dx.doi.org/10.1093/bioinformatics/btq374