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A varying threshold method for ChIP peak-calling using multiple sources of information

Motivation: Gene regulation commonly involves interaction among DNA, proteins and biochemical conditions. Using chromatin immunoprecipitation (ChIP) technologies, protein–DNA interactions are routinely detected in the genome scale. Computational methods that detect weak protein-binding signals and s...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Bei, Zhang, Yu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935431/
https://www.ncbi.nlm.nih.gov/pubmed/20823314
http://dx.doi.org/10.1093/bioinformatics/btq379