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Candidate gene prioritization based on spatially mapped gene expression: an application to XLMR

Motivation: The identification of genes involved in specific phenotypes, such as human hereditary diseases, often requires the time-consuming and expensive examination of a large number of positional candidates selected by genome-wide techniques such as linkage analysis and association studies. Even...

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Detalles Bibliográficos
Autores principales: Piro, Rosario M., Molineris, Ivan, Ala, Ugo, Provero, Paolo, Di Cunto, Ferdinando
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935433/
https://www.ncbi.nlm.nih.gov/pubmed/20823330
http://dx.doi.org/10.1093/bioinformatics/btq396