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Characteristics of 454 pyrosequencing data—enabling realistic simulation with flowsim
Motivation: The commercial launch of 454 pyrosequencing in 2005 was a milestone in genome sequencing in terms of performance and cost. Throughout the three available releases, average read lengths have increased to ∼500 base pairs and are thus approaching read lengths obtained from traditional Sange...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935434/ https://www.ncbi.nlm.nih.gov/pubmed/20823302 http://dx.doi.org/10.1093/bioinformatics/btq365 |