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Maximum likelihood estimation of locus-specific mutation rates in Y-chromosome short tandem repeats
Motivation: Y-chromosome short tandem repeats (Y-STRs) are widely used for population studies, forensic purposes and, potentially, the study of disease, therefore knowledge of their mutation rate is valuable. Here we show a novel method for estimation of site-specific Y-STR mutation rates from parti...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935444/ https://www.ncbi.nlm.nih.gov/pubmed/20823305 http://dx.doi.org/10.1093/bioinformatics/btq367 |