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Automatic policing of biochemical annotations using genomic correlations

With the increasing role of computational tools in the analysis of sequenced genomes, there is an urgent need to maintain high accuracy of functional annotations. Misannotations can be easily generated and propagated through databases by functional transfer based on sequence homology. We developed a...

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Detalles Bibliográficos
Autores principales: Hsiao, Tzu-Lin, Revelles, Olga, Chen, Lifeng, Sauer, Uwe, Vitkup, Dennis
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935526/
https://www.ncbi.nlm.nih.gov/pubmed/19935659
http://dx.doi.org/10.1038/nchembio.266