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Smaller cardiac cell size and reduced extra-cellular collagen might be beneficial for hearts of Ames dwarf mice

Purpose: To test the hypothesis that cardiac morphologic differences between Ames dwarf and wild-type littermates might correlate with the increased longevity observed in the Ames dwarf mice. Methods: Hearts removed from young adult (5-7 mo) and old (24-28 mo) Ames dwarf and wild-type littermates un...

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Detalles Bibliográficos
Autores principales: Helms, Scott A., Azhar, Gohar, Zuo, Chunlai, Theus, Sue A., Bartke, Andrzej, Wei, Jeanne Y.
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935670/
https://www.ncbi.nlm.nih.gov/pubmed/20827400