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Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice

Primary open-angle glaucoma (POAG) is one of the three principal subtypes of glaucoma and among the leading cause of blindness worldwide. POAG is defined by cell death of the retinal ganglion cells (RGCs) and surrounding neuronal cells at higher or normal intraocular pressure (IOP). Coded by one of...

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Detalles Bibliográficos
Autores principales: Chi, Zai-Long, Yasumoto, Fumie, Sergeev, Yuri, Minami, Masayoshi, Obazawa, Minoru, Kimura, Itaru, Takada, Yuichiro, Iwata, Takeshi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935858/
https://www.ncbi.nlm.nih.gov/pubmed/20631153
http://dx.doi.org/10.1093/hmg/ddq299