Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

Reduced brain levels of docosahexaenoic acid (C22:6n-3), a neurotrophic and neuroprotective fatty acid, may contribute to cognitive decline in Alzheimer's disease. Here, we investigated whether the liver enzyme system that provides docosahexaenoic acid to the brain is dysfunctional in this dise...

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Detalles Bibliográficos
Autores principales: Astarita, Giuseppe, Jung, Kwang-Mook, Berchtold, Nicole C., Nguyen, Vinh Q., Gillen, Daniel L., Head, Elizabeth, Cotman, Carl W., Piomelli, Daniele
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935886/
https://www.ncbi.nlm.nih.gov/pubmed/20838618
http://dx.doi.org/10.1371/journal.pone.0012538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935886/
https://www.ncbi.nlm.nih.gov/pubmed/20838618
http://dx.doi.org/10.1371/journal.pone.0012538

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