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Mutational Profiling of Kinases in Human Tumours of Pancreatic Origin Identifies Candidate Cancer Genes in Ductal and Ampulla of Vater Carcinomas

BACKGROUND: Protein kinases are key regulators of cellular processes (such as proliferation, apoptosis and invasion) that are often deregulated in human cancers. Accordingly, kinase genes have been the first to be systematically analyzed in human tumors leading to the discovery that many oncogenes c...

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Detalles Bibliográficos
Autores principales: Corbo, Vincenzo, Ritelli, Rossana, Barbi, Stefano, Funel, Niccola, Campani, Daniela, Bardelli, Alberto, Scarpa, Aldo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935892/
https://www.ncbi.nlm.nih.gov/pubmed/20838624
http://dx.doi.org/10.1371/journal.pone.0012653