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Quiescent hematopoietic stem cells are activated by IFNγ in response to chronic infection

Lymphocytes and neutrophils are rapidly depleted by systemic infection1. Progenitor cells of the hematopoietic system, such as common myeloid progenitors (CMPs) and common lymphoid progenitors (CLPs), increase the production of immune cells to restore and maintain homeostasis during chronic infectio...

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Detalles Bibliográficos
Autores principales: Baldridge, Megan T., King, Katherine Y., Boles, Nathan C., Weksberg, David C., Goodell, Margaret A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935898/
https://www.ncbi.nlm.nih.gov/pubmed/20535209
http://dx.doi.org/10.1038/nature09135