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Therapeutic cell engineering using surface-conjugated synthetic nanoparticles

A major limitation of cell therapies is the rapid decline in viability and function of transplanted cells. Here we describe a strategy to enhance cell therapy via the conjugation of adjuvant drug-loaded nanoparticles to the surfaces of therapeutic cells. Using this method to provide sustained pseudo...

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Detalles Bibliográficos
Autores principales: Stephan, Matthias T., Moon, James J., Um, Soong Ho, Bershteyn, Anna, Irvine, Darrell J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935928/
https://www.ncbi.nlm.nih.gov/pubmed/20711198
http://dx.doi.org/10.1038/nm.2198