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Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

Thyroid hormones have widespread cellular effects; however it is unclear whether their effects on the central nervous system (CNS) contribute to global energy balance. Here, we demonstrate that either whole body hyperthyroidism or central administration of triiodothyronine (T3) decreases the activit...

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Detalles Bibliográficos
Autores principales: López, Miguel, Varela, Luis, Vázquez, María J., Rodríguez-Cuenca, Sergio, González, Carmen R., Velagapudi, Vidya R., Morgan, Donald A., Schoenmakers, Erik, Agassandian, Khristofor, Lage, Ricardo, de Morentin, Pablo Blanco Martínez, Tovar, Sulay, Nogueiras, Rubén, Carling, David, Lelliott, Christopher, Gallego, Rosalía, Orešič, Matej, Chatterjee, Krishna, Saha, Asish K., Rahmouni, Kamal, Diéguez, Carlos, Vidal-Puig, Antonio
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935934/
https://www.ncbi.nlm.nih.gov/pubmed/20802499
http://dx.doi.org/10.1038/nm.2207