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Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
Thyroid hormones have widespread cellular effects; however it is unclear whether their effects on the central nervous system (CNS) contribute to global energy balance. Here, we demonstrate that either whole body hyperthyroidism or central administration of triiodothyronine (T3) decreases the activit...
Autores principales: | López, Miguel, Varela, Luis, Vázquez, María J., Rodríguez-Cuenca, Sergio, González, Carmen R., Velagapudi, Vidya R., Morgan, Donald A., Schoenmakers, Erik, Agassandian, Khristofor, Lage, Ricardo, de Morentin, Pablo Blanco Martínez, Tovar, Sulay, Nogueiras, Rubén, Carling, David, Lelliott, Christopher, Gallego, Rosalía, Orešič, Matej, Chatterjee, Krishna, Saha, Asish K., Rahmouni, Kamal, Diéguez, Carlos, Vidal-Puig, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935934/ https://www.ncbi.nlm.nih.gov/pubmed/20802499 http://dx.doi.org/10.1038/nm.2207 |
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