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Understanding Dermatan Sulfate−Heparin Cofactor II Interaction through Virtual Library Screening

[Image: see text] Dermatan sulfate, an important member of the glycosaminoglycan family, interacts with heparin cofactor II, a member of the serpin family of proteins, to modulate antithrombotic response. Yet, the nature of this interaction remains poorly understood at a molecular level. We report t...

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Detalles Bibliográficos
Autores principales: Raghuraman, Arjun, Mosier, Philip D., Desai, Umesh R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936258/
https://www.ncbi.nlm.nih.gov/pubmed/20835364
http://dx.doi.org/10.1021/ml100048y