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Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis

BACKGROUND: Melanoma vaccines have not been optimized. Adjuvants are added to activate dendritic cells (DCs) and to induce a favourable immunologic milieu, however, little is known about their cellular and molecular effects in human skin. We hypothesized that a vaccine in incomplete Freund's ad...

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Detalles Bibliográficos
Autores principales: Schaefer , Jochen T, Patterson , James W, Deacon , Donna H, Smolkin, Mark E, Petroni , Gina R, Jackson , Emily M, Slingluff, Craig L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936306/
https://www.ncbi.nlm.nih.gov/pubmed/20727190
http://dx.doi.org/10.1186/1479-5876-8-79