Cargando…

Gefitinib radiosensitizes non-small cell lung cancer cells through inhibition of ataxia telangiectasia mutated

PURPOSE: Inhibitors of epidermal growth factor receptor (EGFR) have shown dramatic results in a subset of patients with non-small cell lung cancer (NSCLC), and have also been shown to enhance the effect of ionizing radiation (IR). We investigated how gefitinib, an orally given EGFR inhibitor for NSC...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Soo-Yeon, Kim, Young Mee, Pyo, Hongryull
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936341/
https://www.ncbi.nlm.nih.gov/pubmed/20731837
http://dx.doi.org/10.1186/1476-4598-9-222