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Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia
PRAME/MAPE/OIP4 is a germinal tissue-specific gene that is also expressed at high levels in haematological malignancies and solid tumours. The physiological functions of PRAME in normal and tumour cells are unknown, although a role in the regulation of retinoic acid signalling has been proposed. Seq...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936344/ https://www.ncbi.nlm.nih.gov/pubmed/20799951 http://dx.doi.org/10.1186/1476-4598-9-226 |