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Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism
BACKGROUND: The mechanisms responsible for the cardiovascular mortality in type I diabetes (DM) have not been defined completely. We have shown in conscious dogs with DM that: 1) baseline coronary blood flow (CBF) was significantly decreased, 2) endothelium-dependent (ACh) coronary vasodilation was...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936363/ https://www.ncbi.nlm.nih.gov/pubmed/20735837 http://dx.doi.org/10.1186/1475-2840-9-43 |