Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury

BACKGROUND: Cystic fibrosis is a debilitating lung disease due to mutations in the cystic fibrosis transmembrane conductance regulator protein (CFTR) and is associated with chronic infections resulting in elevated myeloperoxidase activity and generation of hypochlorous acid (HOCl). CFTR mutations le...

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Detalles Bibliográficos
Autores principales: Gould, Neal S, Gauthier, Steve, Kariya, Chirag T, Min, Elysia, Huang, Jie, Brian, Day J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936384/
https://www.ncbi.nlm.nih.gov/pubmed/20799947
http://dx.doi.org/10.1186/1465-9921-11-119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936384/
https://www.ncbi.nlm.nih.gov/pubmed/20799947
http://dx.doi.org/10.1186/1465-9921-11-119

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