Drug-Induced Regulation of Target Expression

Drug perturbations of human cells lead to complex responses upon target binding. One of the known mechanisms is a (positive or negative) feedback loop that adjusts the expression level of the respective target protein. To quantify this mechanism systems-wide in an unbiased way, drug-induced differen...

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Detalles Bibliográficos
Autores principales: Iskar, Murat, Campillos, Monica, Kuhn, Michael, Jensen, Lars Juhl, van Noort, Vera, Bork, Peer
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936514/
https://www.ncbi.nlm.nih.gov/pubmed/20838579
http://dx.doi.org/10.1371/journal.pcbi.1000925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936514/
https://www.ncbi.nlm.nih.gov/pubmed/20838579
http://dx.doi.org/10.1371/journal.pcbi.1000925

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