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An Integrative Multi-Network and Multi-Classifier Approach to Predict Genetic Interactions

Genetic interactions occur when a combination of mutations results in a surprising phenotype. These interactions capture functional redundancy, and thus are important for predicting function, dissecting protein complexes into functional pathways, and exploring the mechanistic underpinnings of common...

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Detalles Bibliográficos
Autores principales: Pandey, Gaurav, Zhang, Bin, Chang, Aaron N., Myers, Chad L., Zhu, Jun, Kumar, Vipin, Schadt, Eric E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936518/
https://www.ncbi.nlm.nih.gov/pubmed/20838583
http://dx.doi.org/10.1371/journal.pcbi.1000928