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Perturbation Analysis of Heterochromatin-Mediated Gene Silencing and Somatic Inheritance
Repetitive sequences in eukaryotic genomes induce chromatin-mediated gene-silencing of juxtaposed genes. Many components that promote or antagonize silencing have been identified, but how heterochromatin causes variegated and heritable changes in gene expression remains mysterious. We have used indu...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936522/ https://www.ncbi.nlm.nih.gov/pubmed/20838586 http://dx.doi.org/10.1371/journal.pgen.1001095 |