Cargando…

Perturbation Analysis of Heterochromatin-Mediated Gene Silencing and Somatic Inheritance

Repetitive sequences in eukaryotic genomes induce chromatin-mediated gene-silencing of juxtaposed genes. Many components that promote or antagonize silencing have been identified, but how heterochromatin causes variegated and heritable changes in gene expression remains mysterious. We have used indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneiderman, Jonathan I., Goldstein, Sara, Ahmad, Kami
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936522/
https://www.ncbi.nlm.nih.gov/pubmed/20838586
http://dx.doi.org/10.1371/journal.pgen.1001095