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Cyclin-Dependent Kinase-Like Function Is Shared by the Beta- and Gamma- Subset of the Conserved Herpesvirus Protein Kinases

The UL97 protein of human cytomegalovirus (HCMV, or HHV-5 (human herpesvirus 5)), is a kinase that phosphorylates the cellular retinoblastoma (Rb) tumor suppressor and lamin A/C proteins that are also substrates of cellular cyclin-dependent kinases (Cdks). A functional complementation assay has furt...

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Detalles Bibliográficos
Autores principales: Kuny, Chad V., Chinchilla, Karen, Culbertson, Michael R., Kalejta, Robert F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936540/
https://www.ncbi.nlm.nih.gov/pubmed/20838604
http://dx.doi.org/10.1371/journal.ppat.1001092