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Chromatin Landscape Dictates HSF Binding to Target DNA Elements

Sequence-specific transcription factors (TFs) are critical for specifying patterns and levels of gene expression, but target DNA elements are not sufficient to specify TF binding in vivo. In eukaryotes, the binding of a TF is in competition with a constellation of other proteins, including histones,...

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Detalles Bibliográficos
Autores principales: Guertin, Michael J., Lis, John T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936546/
https://www.ncbi.nlm.nih.gov/pubmed/20844575
http://dx.doi.org/10.1371/journal.pgen.1001114