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Cyclin-Dependent Kinase Activity Controls the Onset of the HCMV Lytic Cycle

The onset of human cytomegalovirus (HCMV) lytic infection is strictly synchronized with the host cell cycle. Infected G0/G1 cells support viral immediate early (IE) gene expression and proceed to the G1/S boundary where they finally arrest. In contrast, S/G2 cells can be infected but effectively blo...

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Detalles Bibliográficos
Autores principales: Zydek, Martin, Hagemeier, Christian, Wiebusch, Lüder
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936547/
https://www.ncbi.nlm.nih.gov/pubmed/20844576
http://dx.doi.org/10.1371/journal.ppat.1001096