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The Epidermal Growth Factor Receptor (EGFR) Promotes Uptake of Influenza A Viruses (IAV) into Host Cells

Influenza A viruses (IAV) bind to sialic-acids at cellular surfaces and enter cells by using endocytotic routes. There is evidence that this process does not occur constitutively but requires induction of specific cellular signals, including activation of PI3K that promotes virus internalization. Th...

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Detalles Bibliográficos
Autores principales: Eierhoff, Thorsten, Hrincius, Eike R., Rescher, Ursula, Ludwig, Stephan, Ehrhardt, Christina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936548/
https://www.ncbi.nlm.nih.gov/pubmed/20844577
http://dx.doi.org/10.1371/journal.ppat.1001099