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Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein

Many viruses alter expression of proteins on the surface of infected cells including molecules important for immune recognition, such as the major histocompatibility complex (MHC) class I and II molecules. Virus-induced downregulation of surface proteins has been observed to occur by a variety of me...

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Detalles Bibliográficos
Autores principales: Francica, Joseph R., Varela-Rohena, Angel, Medvec, Andrew, Plesa, Gabriela, Riley, James L., Bates, Paul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936550/
https://www.ncbi.nlm.nih.gov/pubmed/20844579
http://dx.doi.org/10.1371/journal.ppat.1001098