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Functional Dichotomy between NKG2D and CD28-Mediated Co-Stimulation in Human CD8(+) T Cells

Both CD28 and NKG2D can function as co-stimulatory receptors in human CD8(+) T cells. However, their independent functional contributions in distinct CD8(+) T cell subsets are not well understood. In this study, CD8(+) T cells in human peripheral blood- and lung-derived lymphocytes were analyzed for...

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Detalles Bibliográficos
Autores principales: Rajasekaran, Kamalakannan, Xiong, Va, Fong, Lee, Gorski, Jack, Malarkannan, Subramaniam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936560/
https://www.ncbi.nlm.nih.gov/pubmed/20844584
http://dx.doi.org/10.1371/journal.pone.0012635