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Single Nucleotide Polymorphisms in the Wnt and BMP Pathways and Colorectal Cancer Risk in a Spanish Cohort

BACKGROUND: Colorectal cancer (CRC) is considered a complex disease, and thus the majority of the genetic susceptibility is thought to lie in the form of low-penetrance variants following a polygenic model of inheritance. Candidate-gene studies have so far been one of the basic approaches taken to i...

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Detalles Bibliográficos
Autores principales: Fernández-Rozadilla, Ceres, de Castro, Luisa, Clofent, Juan, Brea-Fernández, Alejandro, Bessa, Xavier, Abulí, Anna, Andreu, Montserrat, Jover, Rodrigo, Xicola, Rosa, Llor, Xavier, Castells, Antoni, Castellví-Bel, Sergi, Carracedo, Angel, Ruiz-Ponte, Clara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936577/
https://www.ncbi.nlm.nih.gov/pubmed/20844743
http://dx.doi.org/10.1371/journal.pone.0012673