PKCθ is necessary for efficient activation of NFκB, NFAT, and AP-1 during positive selection of thymocytes

While it has been shown in several publications that the serine-threonine kinase PKCθ is required for efficient activation of mature T lymphocytes, the role of PKCθ in T cell development in the thymus is somewhat controversial. In this study, using knockout mice, we show that PKCθ is important in po...

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Detalles Bibliográficos
Autores principales: Gruber, Thomas, Pfeifhofer-Obermair, Christa, Baier, Gottfried
Formato: Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937209/
https://www.ncbi.nlm.nih.gov/pubmed/20433868
http://dx.doi.org/10.1016/j.imlet.2010.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937209/
https://www.ncbi.nlm.nih.gov/pubmed/20433868
http://dx.doi.org/10.1016/j.imlet.2010.04.008

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