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PKCθ is necessary for efficient activation of NFκB, NFAT, and AP-1 during positive selection of thymocytes
While it has been shown in several publications that the serine-threonine kinase PKCθ is required for efficient activation of mature T lymphocytes, the role of PKCθ in T cell development in the thymus is somewhat controversial. In this study, using knockout mice, we show that PKCθ is important in po...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier/North-Holland Biomedical Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937209/ https://www.ncbi.nlm.nih.gov/pubmed/20433868 http://dx.doi.org/10.1016/j.imlet.2010.04.008 |