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The PXR is a drug target for chronic inflammatory liver disease()

PXR activators are used to treat pruritus in chronic inflammatory liver diseases such as primary biliary cirrhosis (PBC). The aims of this study were to determine whether PXR activators could have an additional benefit of inhibiting inflammation in the liver, and determine whether cyclosporin A – wh...

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Detalles Bibliográficos
Autores principales: Wallace, Karen, Cowie, David E., Konstantinou, Dimitrios K., Hill, Stephen J., Tjelle, Torunn E., Axon, Andrew, Koruth, Matthew, White, Steven A., Carlsen, Harald, Mann, Derek A., Wright, Matthew C.
Formato: Texto
Lenguaje:English
Publicado: Pergamon 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937210/
https://www.ncbi.nlm.nih.gov/pubmed/20416375
http://dx.doi.org/10.1016/j.jsbmb.2010.04.012