Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP through MondoA

Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer cells. We compared global transcriptional responses of breast cancer cells in response to three distinct tumor mic...

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Detalles Bibliográficos
Autores principales: Chen, Julia Ling-Yu, Merl, Daniel, Peterson, Christopher W., Wu, Jianli, Liu, Patrick Yantyng, Yin, Hanwei, Muoio, Deborah M., Ayer, Don E., West, Mike, Chi, Jen-Tsan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937306/
https://www.ncbi.nlm.nih.gov/pubmed/20844768
http://dx.doi.org/10.1371/journal.pgen.1001093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937306/
https://www.ncbi.nlm.nih.gov/pubmed/20844768
http://dx.doi.org/10.1371/journal.pgen.1001093

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