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Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP through MondoA
Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer cells. We compared global transcriptional responses of breast cancer cells in response to three distinct tumor mic...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937306/ https://www.ncbi.nlm.nih.gov/pubmed/20844768 http://dx.doi.org/10.1371/journal.pgen.1001093 |