Targeted Deletion of the 9p21 Noncoding Coronary Artery Disease Risk Interval in Mice

Sequence polymorphisms in a 58kb interval on chromosome 9p21 confer a markedly increased risk for coronary artery disease (CAD), the leading cause of death worldwide 1,2. The variants have a substantial impact on the epidemiology of CAD and other life-threatening vascular conditions since nearly a q...

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Detalles Bibliográficos
Autores principales: Visel, Axel, Zhu, Yiwen, May, Dalit, Afzal, Veena, Gong, Elaine, Attanasio, Catia, Blow, Matthew J., Cohen, Jonathan C., Rubin, Edward M., Pennacchio, Len A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938076/
https://www.ncbi.nlm.nih.gov/pubmed/20173736
http://dx.doi.org/10.1038/nature08801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938076/
https://www.ncbi.nlm.nih.gov/pubmed/20173736
http://dx.doi.org/10.1038/nature08801

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